CRISPR‐Net: A Recurrent Convolutional Network Quantifies CRISPR Off‐Target Activities with Mismatches and Indels

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Non-melanoma skin cancer diagnosis with a convolutional neural network

Background: The most common types of non-melanoma skin cancer are basal cell carcinoma (BCC), and squamous cell carcinoma (SCC). AKIEC -Actinic keratoses (Solar keratoses) and intraepithelial carcinoma (Bowen’s disease)- are common non-invasive precursors of SCC, which may progress to invasive SCC, if left untreated. Due to the importance of early detection in cancer treatment, this study aimed...

متن کامل

Music Genre Classification with Paralleling Recurrent Convolutional Neural Network

Deep learning has been demonstrated its effectiveness and efficiency in music genre classification. However, the existing achievements still have several shortcomings which impair the performance of this classification task. In this paper, we propose a hybrid architecture which consists of the paralleling CNN and Bi-RNN blocks. They focus on spatial features and temporal frame orders extraction...

متن کامل

ReNet: A Recurrent Neural Network Based Alternative to Convolutional Networks

In this paper, we propose a deep neural network architecture for object recognition based on recurrent neural networks. The proposed network, called ReNet, replaces the ubiquitous convolution+pooling layer of the deep convolutional neural network with four recurrent neural networks that sweep horizontally and vertically in both directions across the image. We evaluate the proposed ReNet on thre...

متن کامل

CRISP-ID: decoding CRISPR mediated indels by Sanger sequencing

The advent of next generation gene editing technologies has revolutionized the fields of genome engineering in allowing the generation of gene knockout models and functional gene analysis. However, the screening of resultant clones remains challenging due to the simultaneous presence of different indels. Here, we present CRISP-ID, a web application which uses a unique algorithm for genotyping u...

متن کامل

Learning Document Image Features With SqueezeNet Convolutional Neural Network

The classification of various document images is considered an important step towards building a modern digital library or office automation system. Convolutional Neural Network (CNN) classifiers trained with backpropagation are considered to be the current state of the art model for this task. However, there are two major drawbacks for these classifiers: the huge computational power demand for...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Advanced Science

سال: 2020

ISSN: 2198-3844,2198-3844

DOI: 10.1002/advs.201903562